The Wayro route from Fresnillo to Tlaltizapán is 485 miles (780 km), about 8 h 43 min of driving without stops.
| Distance | 485 mi (780 km) |
|---|---|
| Driving time, no stops | 8 h 43 min |
| Main roads, in order | MEX-45 → MEX-45D → MEX-47D → MEX-57D → MEX-57 → Periférico → MEX-95D → MEX-95 → MOR 14 |
| Mexican states on the route | Zacatecas (Level 4), Aguascalientes (Level 2), Jalisco (Level 3), Guanajuato (Level 3), Querétaro (Level 2), State of Mexico (Level 2), Hidalgo (Level 2), Mexico City (Level 2), Morelos (Level 3) |
| Toll roads | MEX-45D, MEX-43D, MEX-47D, MEX-57D, MEX-95D |
| Fuel estimate (car at 25 mpg) | about 19.4 gal; actual use varies by vehicle and traffic |
| Stops listed below | 9 |
Driving this route in a car with U.S. plates
| Temporary vehicle import permit (TIP) | Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora) |
|---|---|
| Mexican auto insurance | Required for all vehicles: buy a Mexican policy before you drive |
Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.
What the drive from Fresnillo to Tlaltizapán is like
MEX-45D (192 mi) and MEX-57D (74 mi) carry about 55% of the 485 miles. MEX-45D, MEX-47D, MEX-57D, MEX-95D are toll highways (cuota); MEX-45, MEX-57, MEX-95 are free federal roads (libre). It runs through 9 states: Zacatecas, Aguascalientes, Jalisco, Guanajuato, Querétaro, State of Mexico, Hidalgo, Mexico City, Morelos. Of the 9 stops listed below, 3 are within a mile of the road.
The route from Fresnillo to Tlaltizapán, road by road
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–1 | 1 | Zacatecas |
| MEX-45 | 1–14 | 13 | Zacatecas |
| MEX-45D | 14–65 | 51 | Zacatecas |
| MEX-45 | 65–93 | 28 | Zacatecas, Aguascalientes |
| local roads | 93–97 | 4 | Aguascalientes |
| MEX-45 | 97–127 | 30 | Aguascalientes, Jalisco |
| MEX-45D | 127–268 | 141 | Jalisco, Guanajuato |
| connecting roads | 268–269 | 1 | Guanajuato |
| MEX-47D | 269–321 | 52 | Guanajuato, Querétaro |
| MEX-57D | 321–395 | 74 | Querétaro, State of Mexico, Hidalgo |
| MEX-57 | 395–403 | 8 | State of Mexico |
| Periférico | 403–422 | 19 | State of Mexico, Mexico City |
| connecting roads | 422–424 | 2 | Mexico City |
| MEX-95D | 424–446 | 22 | Mexico City, Morelos |
| connecting roads | 446–455 | 9 | Morelos |
| MEX-95 | 455–464 | 9 | Morelos |
| MEX-95D | 464–472 | 8 | Morelos |
| connecting roads | 472–473 | 1 | Morelos |
| MOR 14 | 473–480 | 7 | Morelos |
| local roads | 480–485 | 5 | Morelos |
- Mile 70 of this route: Zacatecas → Aguascalientes (state line)
- Mile 124 of this route: Aguascalientes → Jalisco (state line)
- Mile 171 of this route: Jalisco → Guanajuato (state line)
- Mile 281 of this route: Guanajuato → Querétaro (state line)
- Mile 323 of this route: Querétaro → State of Mexico (state line)
- Mile 356 of this route: State of Mexico → Hidalgo (state line)
- Mile 376 of this route: Hidalgo → State of Mexico (state line)
- Mile 408 of this route: State of Mexico → Mexico City (state line)
- Mile 441 of this route: Mexico City → Morelos (state line)
Stops between Fresnillo and Tlaltizapán
- Right off the route (under 1 mile): Aguascalientes Museum (mile 107), Museo Regional de Aguascalientes (mile 108), Templo y exconvento de San Francisco (mile 368)
- Nature and outdoors: Cerro de las Campanas (mile 280), Jardín Edith Sánchez Ramírez (mile 409)
- Museums and history: Guadalupe regional museum (mile 43), Aguascalientes Museum (mile 107), Museo Regional de Aguascalientes (mile 108), Celaya Cathedral (mile 256), Angel of Independence (mile 409), Cuernavaca Cathedral (mile 463)
Guadalupe regional museum
In Guadalupe, Zacatecas, the Museo de Guadalupe fills a former college that sent missionaries to the north and holds an important collection of 17th- to 19th-century painting, including works by Cristóbal de Villalpando, Miguel Cabrera and Juan Correa.
Aguascalientes Museum
Located in the state capital, the Aguascalientes Museum is the city's art museum, set in the city of Aguascalientes, Mexico.
Museo Regional de Aguascalientes
An early 20th-century building by self-taught architect Refugio Reyes holds this INAH museum of Aguascalientes history, with fossils, archaeological finds, colonial paintings by Juan Correa and more than 300 devotional ex-voto paintings.
Celaya Cathedral
Celaya's main Catholic church, the Immaculate Conception Cathedral, occupies the space of a former chapel that was annexed to the neighboring Temple of St. Francis.
Cerro de las Campanas
Rising within Querétaro City, the Cerro de las Campanas is a hill that is protected as a Mexican national park.
Templo y exconvento de San Francisco
The Templo y Exconvento de San Francisco is a church and former convent located in the city of Tepeji del Río, in the Mexican state of Hidalgo.
Angel of Independence
Officially the Monumento a la Independencia, El Ángel is a victory column on Paseo de la Reforma, built in 1910 by architect Antonio Rivas Mercado for the centennial of the start of the War of Independence.
Jardín Edith Sánchez Ramírez
Covering 584 square meters in Colonia Roma, this pocket park fills the triangle formed by Yucatán, San Luis Potosí and Tonalá streets.
Cuernavaca Cathedral
Franciscans built this 16th-century convent church, now Cuernavaca's cathedral and part of the UNESCO-listed monasteries on the slopes of Popocatépetl; visitors can see its murals, side chapels and a sacred art museum.
More drives to Tlaltizapán
- Tetela del Volcán to Tlaltizapán
- Atlixco to Tlaltizapán
- Mexico City to Tlaltizapán
- Metepec to Tlaltizapán
- Zacatelco to Tlaltizapán
- Tlaxcala to Tlaltizapán
From Fresnillo to other places in Mexico
- Fresnillo to Calvillo
- Fresnillo to San Juan de los Lagos
- Fresnillo to Temacapulín
- Fresnillo to Tepatitlán
- Fresnillo to Amatitán
- Fresnillo to Ajijic
Continue Your Adventure
Frequently asked questions
How long is the drive from Fresnillo to Tlaltizapán?
About 8 h 43 min of driving without stops, over 485 miles.
How far is Tlaltizapán from Fresnillo by car?
About 485 miles (780 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Do I need a permit to drive my U.S. car from Fresnillo to Tlaltizapán?
Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.
Is it safe to drive from Fresnillo to Tlaltizapán?
The U.S. State Department rates Zacatecas Level 4: Do Not Travel; Aguascalientes Level 2: Exercise Increased Caution; Jalisco Level 3: Reconsider Travel; Guanajuato Level 3: Reconsider Travel; Querétaro Level 2: Exercise Increased Caution; State of Mexico Level 2: Exercise Increased Caution; Hidalgo Level 2: Exercise Increased Caution; Mexico City Level 2: Exercise Increased Caution; Morelos Level 3: Reconsider Travel (advisory issued May 29, 2026). Read the full advisory before you go.
What roads does the drive from Fresnillo to Tlaltizapán use?
In order: MEX-45, MEX-45D, MEX-47D, MEX-57D, MEX-57, Periférico, MEX-95D, MEX-95 and MOR 14. The road-by-road table above shows the route miles and states for each one.
What are good stops between Fresnillo and Tlaltizapán?
Closest to the road: Aguascalientes Museum (art museum, mile 107, 0.4 mi from the route); Museo Regional de Aguascalientes (history museum, mile 108, 0.3 mi from the route); Templo y exconvento de San Francisco (convent, mile 368, 0.6 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway mile markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route (roughly 2 to 7 miles depending on the type, farther for World Heritage sites): at least one strong stop for each stretch of the drive, then the best-known places nearest the road, with no more than five of one type, up to nine in all. Places that are closed, private or not open to visitors are removed. Place and city descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.