The Wayro route from Florianópolis to Santos is 423 miles (680 km), about 9 h 19 min of driving without stops.
- Level 4: Do Not Travel in Brazil: informal housing developments (favelas, vilas, comunidades or conglomerados).
Full advisory: Brazil. Advisory issued: Brazil August 31, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Brazil: “Drivers must have their daytime running lights on during the day and headlights on at night on Federal Highways.”
| Distance by road | 423 mi (680 km) |
|---|---|
| Time at the wheel, no stops | 9 h 19 min |
| Main roads, in order | BR-282 → BR-101 → BR-376 → BR-116 → SP-055 → SPA-291/055 |
| States on the route | Santa Catarina, Paraná, São Paulo |
| Fuel estimate (car at 25 mpg) | about 16.9 gal; actual use varies by vehicle and traffic |
| Stops listed below | 9 |
The Florianópolis–Santos drive in a few lines
BR-116 (173 mi) and BR-101 (127 mi) carry about 71% of the 423 miles. It runs through 3 states: Santa Catarina, Paraná, São Paulo. Of the 9 stops listed below, 1 are within a mile of the road.
Florianópolis to Santos: the road sequence
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–2 | 2 | |
| BR-282 | 2–5 | 3 | Santa Catarina |
| connecting roads | 5–6 | 1 | Santa Catarina |
| BR-101 | 6–133 | 127 | Santa Catarina |
| BR-376 | 133–175 | 42 | Santa Catarina, Paraná |
| BR-116 | 175–348 | 173 | Paraná, São Paulo |
| SP-055 | 348–409 | 61 | São Paulo |
| SPA-291/055 | 409–417 | 8 | São Paulo |
| local roads | 417–423 | 6 | São Paulo |
- Mile 134 of this route: Santa Catarina → Paraná (state line)
- Mile 240 of this route: Paraná → São Paulo (state line)
Places worth a stop between Florianópolis and Santos
- Right off the route (under 1 mile): Praia da Ilhota (mile 43)
- Nature and outdoors: Praia da Ilhota (mile 43), Praia das Taquaras (mile 47), Pico Paraná State Park (mile 208), Rio Turvo State Park (mile 267), Campina do Encantado State Park (mile 303), Itinguçu State Park (mile 370)
- Museums and history: Museu Casa Fritz Alt (mile 107), Museu Municipal Atílio Rocco (mile 176), Itaipu Fortress (mile 416)
Praia da Ilhota
On Itapema's coast in Santa Catarina, Praia da Ilhota pairs clear water and a wide strip of coarse golden sand with a string of seafood spots, and its slightly choppy sea draws local surfers.
Praia das Taquaras
Reached by the Interpraias road, Praia das Taquaras (Praia de Taquaras) in Balneário Camboriú has about 1.1 km of coarse sand and calm but deep water, popular for surf casting, plus a small fishing community.
Museu Casa Fritz Alt
Artist Fritz Alt's 1940s home in Joinville opened as a museum in 1975; its setting on Morro do Boa Vista gives visitors a panoramic view of the city.
Museu Municipal Atílio Rocco
Founded on September 19, 1977, by Ernani Zetola, Museu Municipal Atílio Rocco is a city-run cultural institution in São José dos Pinhais, Paraná.
Pico Paraná State Park
Pico Paraná State Park protects well-preserved Atlantic Forest in Paraná state and contains a massif with the highest peak in southern Brazil.
Rio Turvo State Park
Roughly 73,900 hectares of Atlantic Forest fall within Rio Turvo State Park, which reaches into Cajati, Barra do Turvo and Jacupiranga. It has trails, a waterfall, a cave and Morro do Guaraú.
Campina do Encantado State Park
Campina do Encantado State Park, in the São Paulo state town of Pariquera-Açu, protects a peat bog and a patch of wetland forest, described as a unique ecosystem of great scientific interest.
Itinguçu State Park
Itinguçu State Park is a state park in the state of São Paulo, Brazil.
Itaipu Fortress
Known as Itaipu Fortress, Forte Duque de Caxias de Itaipu sits on Ponta de Itaipu in Praia Grande, overlooking the São Vicente bar on the São Paulo coast.
Arriving in Santos
Praia do Guaiuba
With fine, light-colored sand stretching about 790 meters, Praia do Guaiúba is a beach in Guarujá, São Paulo.
Góis Beach
Fishing families make up most of the community at Góis Beach (Praia do Góis), a 250-meter beach in Guarujá, São Paulo, ringed by hills covered in Atlantic Forest.
Our Lady of the Rosary Cathedral, Santos
Also known as Santos Cathedral, Our Lady of the Rosary Cathedral is a Catholic church in the city of Santos, in São Paulo State, Brazil.
More drives to Santos
- São Paulo to Santos
- Jundiaí to Santos
- Campinas to Santos
- Ribeirão Preto to Santos
- Uberlândia to Santos
- Mogi das Cruzes to Santos
From Florianópolis to other places in Brazil
- Florianópolis to Jaraguá do Sul
- Florianópolis to Paranaguá
- Florianópolis to Ponta Grossa
- Florianópolis to Caxias do Sul
- Florianópolis to Novo Hamburgo
- Florianópolis to Bento Gonçalves
Frequently asked questions
How long does it take to drive from Florianópolis to Santos?
About 9 h 19 min of driving without stops, over 423 miles.
How far is Santos from Florianópolis by car?
About 423 miles (680 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Is it safe to drive from Florianópolis to Santos?
The U.S. State Department rates Brazil Level 2: Exercise Increased Caution. Read the full advisory before you go.
Which highways go from Florianópolis to Santos?
In order: BR-282, BR-101, BR-376, BR-116, SP-055 and SPA-291/055. The road-by-road table above shows the route miles for each one.
What are good stops between Florianópolis and Santos?
Closest to the road: Praia da Ilhota (beach, mile 43, 0.2 mi from the route); Praia das Taquaras (beach, mile 47, 2 mi from the route); Itaipu Fortress (fortress, mile 416, 1 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.