Comala to Xilitla is about 455 road miles (732 km): roughly 10 h 54 min at the wheel if you don't stop.
| Distance by road | 455 mi (732 km) |
|---|---|
| Driving time, no stops | 10 h 54 min |
| Main roads, in order | MEX-54 → MEX-54D → MEX-110 → MEX-15 → MEX-35 → MEX-90 → MEX-45D → MEX-57D → QRO 4 → QRO 100 → MEX-120 |
| Mexican states on the route | Colima, Jalisco, Michoacán, Guanajuato, Querétaro, San Luis Potosí |
| Toll roads (as marked in OpenStreetMap) | MEX-54D, MEX-45D, MEX-57D |
| Fuel estimate (car at 25 mpg) | about 18.2 gal; actual use varies by vehicle and traffic |
| Stops listed below | 8 |
Driving this route in a car with U.S. plates
| Temporary vehicle import permit (TIP) | Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora) |
|---|---|
| Mexican auto insurance | Required for all vehicles: buy a Mexican policy before you drive |
Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.
How the Comala to Xilitla drive plays out
MEX-110 (121 mi) and MEX-120 (105 mi) carry about 50% of the 455 miles. It runs through 6 states: Colima, Jalisco, Michoacán, Guanajuato, Querétaro, San Luis Potosí. OpenStreetMap marks tolled sections on MEX-54D, MEX-45D and MEX-57D. Of the 8 stops listed below, 1 are within a mile of the road.
Comala to Xilitla: the road sequence
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–7 | 7 | Colima |
| MEX-54 | 7–11 | 4 | Colima |
| MEX-54D | 11–35 | 24 | Colima, Jalisco |
| MEX-54 | 35–45 | 10 | Jalisco |
| MEX-110 | 45–110 | 65 | Jalisco, Michoacán |
| connecting roads | 110–112 | 2 | Michoacán |
| MEX-15 | 112–117 | 5 | Michoacán |
| MEX-110 | 117–135 | 18 | Michoacán |
| MEX-35 | 135–142 | 7 | Michoacán |
| MEX-110 | 142–180 | 38 | Michoacán, Guanajuato |
| MEX-90 | 180–226 | 46 | Guanajuato |
| MEX-45D | 226–293 | 67 | Guanajuato, Querétaro |
| MEX-57D | 293–303 | 10 | Querétaro |
| QRO 4 | 303–323 | 20 | Querétaro |
| QRO 100 | 323–332 | 9 | Querétaro |
| local roads | 332–337 | 5 | Querétaro |
| QRO 100 | 337–350 | 13 | Querétaro |
| MEX-120 | 350–455 | 105 | Querétaro, San Luis Potosí |
- Mile 21 of this route: Colima → Jalisco (state line)
- Mile 88 of this route: Jalisco → Michoacán (state line)
- Mile 170 of this route: Michoacán → Guanajuato (state line)
- Mile 285 of this route: Guanajuato → Querétaro (state line)
- Mile 440 of this route: Querétaro → San Luis Potosí (state line)
Breaking up the drive: stops between Comala and Xilitla
- Right off the route (under 1 mile): Santa María del Agua de Landa mission (mile 417)
- Nature and outdoors: Volcán Nevado de Colima National Park (mile 25), El Cimatario National Park (mile 296)
- Museums and history: Plazuelas (mile 188), Irapuato Cathedral (mile 227), Querétaro Cathedral (mile 291), Queretaro Art Museum (mile 291), Santa María del Agua de Landa mission (mile 417), San Francisco del Valle de Tilaco mission (mile 434)
Volcán Nevado de Colima National Park
This national park in western Mexico protects the upper slopes of two volcanic peaks, Volcán de Colima and Nevado de Colima, in the states of Jalisco and Colima.
Plazuelas
Near Pénjamo, Plazuelas flourished between AD 450 and 700. Trails lead to Casas Tapadas, a platform crowned by four pyramid bases, a ball court, and rocks carved with spirals and La Maqueta, a low-relief model of Casas Tapadas.
Irapuato Cathedral
Irapuato's cathedral, dedicated to the Immaculate Conception, dates from the 18th century and has a Baroque facade. It served as the seat of the local parish until 2004, when the new Diocese of Irapuato made it a cathedral.
Querétaro Cathedral
Querétaro's cathedral, dedicated to St. Philip Neri, is a Catholic church built by the Oratory of Saint Philip Neri in Santiago de Querétaro.
Queretaro Art Museum
Set in the cloister of the former San Agustín convent, the Museo de Arte de Querétaro opened in 1988 and shows paintings and sculpture across fifteen galleries.
El Cimatario National Park
El Cimatario National Park protects about 24 square kilometers of land just south of the city of Santiago de Querétaro.
Santa María del Agua de Landa mission
Built by Franciscans in the 18th century, the Mission of Santa María del Agua de Landa in Landa de Matamoros is an architectural complex in the churrigueresque style.
San Francisco del Valle de Tilaco mission
In Landa de Matamoros, the Misión de San Francisco de Asís del Valle de Tilaco has a Baroque facade, one of the last works in that style built in New Spain, and is a key monument of the Sierra Gorda.
Arriving in Xilitla
Las Pozas
Created by Edward James in the Sierra Gorda, Las Pozas is a surrealist sculpture garden where concrete structures stand among waterfalls and pools in subtropical forest.
More drives to Xilitla
- Pedro Escobedo to Xilitla
- Tulancingo to Xilitla
- Actopan to Xilitla
- Otumba to Xilitla
- Celaya to Xilitla
- San Miguel de Allende to Xilitla
From Comala to other places in Mexico
- Comala to Temacapulín
- Comala to Pabellón de Hidalgo
- Comala to San José de Gracia, Aguascalientes
- Comala to Real de Asientos
- Comala to Pinos
- Comala to Bernal
Continue Your Adventure
Frequently asked questions
How long does it take to drive from Comala to Xilitla?
About 10 h 54 min of driving without stops, over 455 miles.
How far is Xilitla from Comala by car?
About 455 miles (732 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Do I need a permit to drive my U.S. car from Comala to Xilitla?
Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.
Is it safe to drive from Comala to Xilitla?
The U.S. State Department rates Colima Level 4: Do Not Travel; Jalisco Level 3: Reconsider Travel; Michoacán Level 4: Do Not Travel; Guanajuato Level 3: Reconsider Travel; Querétaro Level 2: Exercise Increased Caution; San Luis Potosí Level 2: Exercise Increased Caution (advisory issued May 29, 2026). Read the full advisory before you go.
Which highways go from Comala to Xilitla?
In order: MEX-54, MEX-54D, MEX-110, MEX-15, MEX-35, MEX-90, MEX-45D, MEX-57D, QRO 4, QRO 100 and MEX-120. The road-by-road table above shows the route miles for each one.
Where can you stop on the way from Comala to Xilitla?
Closest to the road: Queretaro Art Museum (art museum, mile 291, 1 mi from the route); Querétaro Cathedral (cathedral, mile 291, 1 mi from the route); Santa María del Agua de Landa mission (mission, mile 417, 1 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.