Colón, Argentina to Chuy, Uruguay Road Trip: Route & Border

By admin, 13 October, 2026

The Wayro route from Colón, Argentina to Chuy, Uruguay is 429 miles (691 km), about 9 h 8 min of driving without stops. You cross from Argentina into Uruguay at about mile 6, at the Colón–Paysandú bridge.

U.S. State Department travel advisory: Argentina — Level 1, Exercise Normal Precautions; Uruguay — Level 2, Exercise Increased Caution

Full advisory: Argentina, Uruguay. Advisory issued: Argentina July 10, 2026; Uruguay July 28, 2026; checked October 10, 2026.

On the roads, the State Department says:

  • Argentina: “Drivers should prepare in advance when taking long road trips and make sure to have adequate insurance coverage.”
  • Uruguay: “Traffic fatalities are high in Uruguay.”
Nuestra Señora del Rosario y San Benito de Palermo, PaysandúReserva de Flora y fauna Dr. Rodolfo TáliceCathedral of San José de MayoCathedral of Our Lady of GuadalupeCerro Pan de Azúcar Native Wildlife Breeding StationLaguna José IgnacioTeatro 25 de MayoSanta Teresa National ParkParque Nacional Laguna NegraArgentina–Uruguay borderColónChuy
Route from Colón to Chuy with the 9 stops listed below (blue dots) and the approximate Argentina–Uruguay border crossing (red square).
Distance429 mi (691 km)
Time at the wheel, no stops9 h 8 min
Main roads, in orderI-B
Border crossingabout mile 6, Argentina → Uruguay (the Colón–Paysandú bridge)
Regions on the routeEntre Ríos, Paysandú, Río Negro, Flores, San José, Canelones, Maldonado, Rocha
Fuel estimate (car at 25 mpg)about 17.2 gal; actual use varies by vehicle and traffic
Stops listed below9

Crossing from Argentina into Uruguay

The route crosses at about mile 6, at the Colón–Paysandú bridge, from Entre Ríos into Paysandú. Plan on two checks on each side: immigration for your passport and customs for the car.

Entering Uruguay (U.S. citizens)No visa needed for visits of 90 days or less. Passport: must be valid for 6 months beyond your arrival date.
Driving in UruguayYou can drive on your U.S. license.
Entering Argentina (U.S. citizens)No visa needed for visits of 90 days or less. Passport: must be valid when you enter; leave a blank page for the entry and exit stamps.
Driving in ArgentinaA valid U.S. license usually works; an International Driving Permit is recommended.
Rental carCross only if the rental company authorizes it in writing and gives you the papers for the border; ask before you book.

Sources: U.S. State Department, Uruguay (updated August 13, 2026); U.S. State Department, Argentina (updated July 16, 2026). Checked October 10, 2026; rules change, so confirm before you go.

Driving Colón to Chuy: the shape of the trip

I-B (6 mi) carries about 1% of the 429 miles. The first 6 miles are in Argentina; the last 423 are in Uruguay. It runs through 8 regions: Entre Ríos, Paysandú, Río Negro, Flores, San José, Canelones, Maldonado, Rocha. Of the 9 stops listed below, 4 are within a mile of the road.

The route from Colón to Chuy, road by road

RoadRoute miles (from–to)Length, miRegion
local roads0–279279Entre Ríos, Paysandú, Río Negro, Flores, San José, Canelones, Maldonado
I-B279–2856Maldonado
local roads285–429144Maldonado, Rocha
  • Mile 6 of this route: Entre Ríos → Paysandú (international border)
  • Mile 39 of this route: Paysandú → Río Negro (region line)
  • Mile 94 of this route: Río Negro → Flores (region line)
  • Mile 155 of this route: Flores → San José (region line)
  • Mile 204 of this route: San José → Canelones (region line)
  • Mile 274 of this route: Canelones → Maldonado (region line)
  • Mile 331 of this route: Maldonado → Rocha (region line)

Where to stop on the way to Chuy

  • Right off the route (under 1 mile): Reserva de Flora y fauna Dr. Rodolfo Tálice (mile 122), Cathedral of Our Lady of Guadalupe (mile 215), Teatro 25 de Mayo (mile 349), Santa Teresa National Park (mile 408)
  • Nature and outdoors: Reserva de Flora y fauna Dr. Rodolfo Tálice (mile 122), Cerro Pan de Azúcar Native Wildlife Breeding Station (mile 285), Laguna José Ignacio (mile 319), Santa Teresa National Park (mile 408)
  • Museums and history: Nuestra Señora del Rosario y San Benito de Palermo, Paysandú (mile 13), Cathedral of San José de Mayo (mile 185), Cathedral of Our Lady of Guadalupe (mile 215)

Nuestra Señora del Rosario y San Benito de Palermo, Paysandú

Mile 13 · Basilica · 2 mi from the route

Paysandú's Catholic parish church of Our Lady of the Rosary and St. Benedict of Palermo was named a minor basilica in 1949 and remains an active parish of the city.

Reserva de Flora y fauna Dr. Rodolfo Tálice

Mile 122 · Botanical garden · 0.1 mi from the route

Off Route 3 near Trinidad, the Dr. Rodolfo Tálice Ecopark (Reserva de Flora y Fauna Dr. Rodolfo Talice) is a fenced wildlife reserve where axis deer, greater rheas and pampas deer roam free alongside other species.

Cathedral of San José de Mayo

Mile 185 · Cathedral · 2 mi from the route

The main Catholic church of San José de Mayo, the Cathedral Basilica of St. Joseph has been the diocesan seat since 1955, a minor basilica since 1957 and Uruguay's national shrine of Saint Joseph.

Cathedral of Our Lady of Guadalupe

Mile 215 · Cathedral · 0.2 mi from the route

Construction of Canelones' Cathedral of Our Lady of Guadalupe began in 1816; the church became a cathedral in 1961 and Uruguay's national shrine of Our Lady of Guadalupe in 2020.

Cerro Pan de Azúcar Native Wildlife Breeding Station

Mile 285 · Nature park · 2 mi from the route · side trip; actual detour depends on access roads

Near Piriápolis in Maldonado, this breeding station for native wildlife on Cerro Pan de Azúcar is surrounded by native vegetation and offers guided visits, including a native wildlife trail and a path up the hill.

Laguna José Ignacio

Mile 319 · Lagoon · 5 mi from the route · side trip; actual detour depends on access roads

In Uruguay's Maldonado Department, Laguna José Ignacio is a coastal lagoon kept apart from the Atlantic Ocean by a sandbank.

Teatro 25 de Mayo

Mile 349 · Theater · 1 mi from the route

Rocha's Teatro 25 de Mayo opened in 1910 as an Italian-style theater in the eclectic style, with room for about 400 people. Now a cultural complex, it is a stop on the city's self-guided heritage walk.

Santa Teresa National Park

Mile 408 · National park · 0.1 mi from the route

Santa Teresa National Park on Rocha's coast was created to frame the colonial Santa Teresa Fortress; its grounds hold more than two million planted trees from five continents, a greenhouse and native wetland and woodland wildlife.

Parque Nacional Laguna Negra

Mile 409 · Nature area · 4 mi from the route · side trip; actual detour depends on access roads

In Rocha department, Laguna Negra National Park protects the waters of Laguna Negra, the Potrerillo de Santa Teresa biological station and part of Santa Teresa National Park north of Route 9.

More drives to Chuy

More drives from Colón

Frequently asked questions

How long does it take to drive from Colón, Argentina to Chuy, Uruguay?

About 9 h 8 min of driving without stops, over 429 miles.

How far is Chuy, Uruguay from Colón, Argentina by car?

About 429 miles (691 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.

Where does the Colón to Chuy drive cross the border?

At about mile 6, from Argentina into Uruguay, at the Colón–Paysandú bridge.

What do U.S. citizens need to drive from Colón into Uruguay?

No visa needed for visits of 90 days or less. Passport: must be valid for 6 months beyond your arrival date. You can drive on your U.S. license. (U.S. State Department, updated August 13, 2026.)

What does the U.S. travel advisory say about the Colón to Chuy drive?

The U.S. State Department rates Argentina Level 1: Exercise Normal Precautions; Uruguay Level 2: Exercise Increased Caution. Read the full advisory before you go.

Where can you stop on the way from Colón to Chuy?

Closest to the road: Reserva de Flora y fauna Dr. Rodolfo Tálice (botanical garden, mile 122, 0.1 mi from the route); Cathedral of Our Lady of Guadalupe (cathedral, mile 215, 0.2 mi from the route); Santa Teresa National Park (national park, mile 408, 0.1 mi from the route). All stops are described above.

How we put this guide together

Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.

Route data © OpenStreetMap contributors.