Cholula to Santa Catarina Juquila Road Trip: Stops & Tolls

By admin, 13 October, 2026

By road, Cholula and Santa Catarina Juquila are about 335 miles (539 km) apart, or roughly 6 h 35 min of driving.

U.S. State Department travel advisory: Puebla — Level 2, Exercise Increased Caution; Oaxaca — Level 2, Exercise Increased CautionAdvisory issued May 29, 2026; checked September 29, 2026. Oaxaca is the Mexican state that contains Santa Catarina Juquila. See the full advisory for current details.
Museo Nacional de los Ferrocarriles MexicanosCasa del AlfeñiqueTehuacán-Cuicatlán Biosphere ReserveSuchilquitongoBenito Juárez National ParkChurch of Santo Domingo de GuzmánMonastery of Santiago Apóstol, Cuilapan de GuerreroZaachilaCholulaSanta Catarina Juquila
Route from Cholula to Santa Catarina Juquila with the 8 stops listed below (blue dots).
Distance by road335 mi (539 km)
Drive time without stops6 h 35 min
Main roads, in orderMEX-190 → MEX-150D → MEX-135D → MEX-131
Mexican states on the routePuebla, Oaxaca
Toll roads (as marked in OpenStreetMap)MEX-150D, MEX-135D
Fuel estimate (car at 25 mpg)about 13.4 gal; actual use varies by vehicle and traffic
Stops listed below8

Driving this route in a car with U.S. plates

Temporary vehicle import permit (TIP)Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora)
Mexican auto insuranceRequired for all vehicles: buy a Mexican policy before you drive

Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.

How the Cholula to Santa Catarina Juquila drive plays out

MEX-135D (151 mi) and MEX-131 (82 mi) carry about 70% of the 335 miles. It runs through 2 states: Puebla, Oaxaca. OpenStreetMap marks tolled sections on MEX-150D and MEX-135D. Of the 8 stops listed below, 4 are within a mile of the road.

Which roads connect Cholula and Santa Catarina Juquila

RoadRoute miles (from–to)Length, miState
local roads0–11Puebla
MEX-1901–54Puebla
connecting roads5–61Puebla
local roads6–104Puebla
connecting roads10–122Puebla
MEX-150D12–5846Puebla
MEX-135D58–209151Puebla, Oaxaca
MEX-190209–2156Oaxaca
local roads215–23116Oaxaca
MEX-131231–25423Oaxaca
local roads254–2573Oaxaca
MEX-131257–31659Oaxaca
local roads316–33519Oaxaca
  • Mile 111 of this route: Puebla → Oaxaca (state line)

Stops between Cholula and Santa Catarina Juquila

  • Right off the route (under 1 mile): Museo Nacional de los Ferrocarriles Mexicanos (mile 7), Suchilquitongo (mile 198), Church of Santo Domingo de Guzmán (mile 217), Zaachila (mile 224)
  • Nature and outdoors: Tehuacán-Cuicatlán Biosphere Reserve (mile 102), Benito Juárez National Park (mile 209)
  • Museums and history: Museo Nacional de los Ferrocarriles Mexicanos (mile 7), Casa del Alfeñique (mile 7), Suchilquitongo (mile 198), Church of Santo Domingo de Guzmán (mile 217), Zaachila (mile 224)

Museo Nacional de los Ferrocarriles Mexicanos

Mile 7 · Railway museum · 0.5 mi from the route

In Puebla's historic center, this national railway museum studies, preserves and shares Mexico's railroad heritage through exhibits on the history of the trains.

Casa del Alfeñique

Mile 7 · Museum · 1 mi from the route

Founded in 1926, the Museo Regional Casa de Alfeñique is a museum in the city of Puebla, housed in the building known as the Casa de Alfeñique.

Tehuacán-Cuicatlán Biosphere Reserve

Mile 102 · Biosphere reserve · 7 mi from the route · side trip; actual detour depends on access roads

In 2018 UNESCO inscribed the arid Tehuacán-Cuicatlán Valley, which spans Puebla and Oaxaca, as a mixed World Heritage site. A major center of cactus diversity, it also keeps ancient canals, terraces and dams.

Suchilquitongo

Mile 198 · Archaeological site · 0.4 mi from the route

From around 300 to 800 AD, a Zapotec city thrived on a hilltop in the northern Etla Valley. Locals know the site as Cerro de la Campana.

Benito Juárez National Park

Mile 209 · National park · 3 mi from the route · side trip; actual detour depends on access roads

Pine and oak forest covers about 2,737 hectares in Benito Juárez National Park, a short way north of Oaxaca City. Among its trails is La Coronilla, a loop of around 5 km at moderate difficulty.

Church of Santo Domingo de Guzmán

Mile 217 · Church · 1 mi from the route

An example of New Spanish Baroque architecture, the Church and Convent of Santo Domingo de Guzmán in Oaxaca de Juárez traces back to 1551, when the city council granted 24 lots to the Dominican Order for a convent.

Monastery of Santiago Apóstol, Cuilapan de Guerrero

Mile 222 · Monastery · 2 mi from the route · side trip; actual detour depends on access roads

In the town of Cuilapan de Guerrero, the fortress-like former monastery of Santiago Apóstol is easy to spot from the highway south of Oaxaca City toward Villa de Zaachila and draws Mexican and international visitors.

Zaachila

Mile 224 · Archaeological site · 0.4 mi from the route

Occupied as far back as about 1500 BC, Zaachila was a Zapotec city, later shared with Mixtecs. People still lived there when the Spanish arrived.

More drives to Santa Catarina Juquila

From Cholula to other places in Mexico

Frequently asked questions

How long does it take to drive from Cholula to Santa Catarina Juquila?

About 6 h 35 min of driving without stops, over 335 miles.

What is the driving distance from Cholula to Santa Catarina Juquila?

About 335 miles (539 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.

Do I need a permit to drive my U.S. car from Cholula to Santa Catarina Juquila?

Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.

Is it safe to drive from Cholula to Santa Catarina Juquila?

The U.S. State Department rates Puebla Level 2: Exercise Increased Caution; Oaxaca Level 2: Exercise Increased Caution (advisory issued May 29, 2026). Read the full advisory before you go.

Which highways go from Cholula to Santa Catarina Juquila?

In order: MEX-190, MEX-150D, MEX-135D and MEX-131. The road-by-road table above shows the route miles for each one.

What are good stops between Cholula and Santa Catarina Juquila?

Closest to the road: Museo Nacional de los Ferrocarriles Mexicanos (railway museum, mile 7, 0.5 mi from the route); Suchilquitongo (archaeological site, mile 198, 0.4 mi from the route); Zaachila (archaeological site, mile 224, 0.4 mi from the route). All stops are described above.

How we put this guide together

Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.

Route data © OpenStreetMap contributors.