Cholula to Huatulco Road Trip: Where to Stop on the Way

By admin, 13 October, 2026

Cholula to Huatulco is about 393 road miles (632 km): roughly 7 h 11 min at the wheel if you don't stop.

U.S. State Department travel advisory: Puebla — Level 2, Exercise Increased Caution; Oaxaca — Level 2, Exercise Increased CautionAdvisory issued May 29, 2026; checked September 29, 2026. Oaxaca is the Mexican state that contains Huatulco. See the full advisory for current details.
Museo Nacional de los Ferrocarriles MexicanosCasa del DeánMuseo del Valle de TehuacánTehuacán-Cuicatlán Biosphere ReserveBenito Juárez National ParkMuseo Rufino Tamayo, OaxacaHistoric centre of OaxacaZaachilaMermejitaCholulaHuatulco
Route from Cholula to Huatulco with the 9 stops listed below (blue dots).
Total distance393 mi (632 km)
Driving time, no stops7 h 11 min
Main roads, in orderMEX-190 → MEX-150D → MEX-135D → MEX-175 → MEX-175D → MEX-200
Mexican states on the routePuebla, Oaxaca
Toll roads (as marked in OpenStreetMap)MEX-150D, MEX-135D, MEX-175D
Fuel estimate (car at 25 mpg)about 15.7 gal; actual use varies by vehicle and traffic
Stops listed below9

Driving this route in a car with U.S. plates

Temporary vehicle import permit (TIP)Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora)
Mexican auto insuranceRequired for all vehicles: buy a Mexican policy before you drive

Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.

What the drive from Cholula to Huatulco is like

MEX-135D (151 mi) and MEX-175D (64 mi) carry about 55% of the 393 miles. It runs through 2 states: Puebla, Oaxaca. OpenStreetMap marks tolled sections on MEX-150D, MEX-135D and MEX-175D. Of the 9 stops listed below, 3 are within a mile of the road.

Cholula to Huatulco: the road sequence

RoadRoute miles (from–to)Length, miState
local roads0–11Puebla
MEX-1901–54Puebla
connecting roads5–61Puebla
local roads6–104Puebla
connecting roads10–122Puebla
MEX-150D12–5846Puebla
MEX-135D58–209151Puebla, Oaxaca
MEX-190209–2156Oaxaca
local roads215–2216Oaxaca
MEX-175221–23211Oaxaca
local roads232–24210Oaxaca
MEX-175242–25412Oaxaca
local roads254–2606Oaxaca
connecting roads260–2655Oaxaca
MEX-175D265–32964Oaxaca
MEX-200329–39061Oaxaca
local roads390–3933Oaxaca
  • Mile 111 of this route: Puebla → Oaxaca (state line)

Places worth a stop between Cholula and Huatulco

  • Right off the route (under 1 mile): Museo Nacional de los Ferrocarriles Mexicanos (mile 7), Museo Rufino Tamayo, Oaxaca (mile 216), Historic centre of Oaxaca (mile 217)
  • Nature and outdoors: Tehuacán-Cuicatlán Biosphere Reserve (mile 102), Benito Juárez National Park (mile 209), Mermejita (mile 357)
  • Museums and history: Museo Nacional de los Ferrocarriles Mexicanos (mile 7), Casa del Deán (mile 7), Museo del Valle de Tehuacán (mile 87), Museo Rufino Tamayo, Oaxaca (mile 216), Historic centre of Oaxaca (mile 217), Zaachila (mile 225)

Museo Nacional de los Ferrocarriles Mexicanos

Mile 7 · Railway museum · 0.5 mi from the route

In Puebla's historic center, this national railway museum studies, preserves and shares Mexico's railroad heritage through exhibits on the history of the trains.

Casa del Deán

Mile 7 · Historic house museum · 1 mi from the route

Built in 1563 for Tomás de la Plaza y Goes, dean of Puebla Cathedral, the Casa del Deán is a historic house in Puebla that takes its name from his post.

Museo del Valle de Tehuacán

Mile 87 · Museum · 3 mi from the route · side trip; actual detour depends on access roads

The history of corn and how it connects to the valley's early peoples is the focus of the Valley of Tehuacán Museum, which opened in 2002 in a former Carmelite convent.

Tehuacán-Cuicatlán Biosphere Reserve

Mile 102 · Biosphere reserve · 7 mi from the route · side trip; actual detour depends on access roads

This arid valley straddling Puebla and Oaxaca joined UNESCO's World Heritage List in 2018 as a mixed site. It is a major center of cactus diversity and preserves ancient canals, wells, terraces and dams built to manage scarce water.

Benito Juárez National Park

Mile 209 · National park · 3 mi from the route · side trip; actual detour depends on access roads

Hikers heading just north of Oaxaca City reach Benito Juárez National Park, where trails cross roughly 2,737 hectares of pine and oak. La Coronilla, a moderate loop, runs about 5 km.

Museo Rufino Tamayo, Oaxaca

Mile 216 · Art museum · 0.7 mi from the route

The Museo Rufino Tamayo is an art museum you can visit in the city of Oaxaca, in southern Mexico.

Historic centre of Oaxaca

Mile 217 · Historic center · 0.9 mi from the route

The historic center of Oaxaca de Juárez has been a UNESCO World Heritage Site since 1987, listed together with the archaeological site of Monte Albán as an example of Spanish colonial town planning.

Zaachila

Mile 225 · Archaeological site · 3 mi from the route · side trip; actual detour depends on access roads

Zaachila was a Zapotec city, later shared with Mixtecs, that was still inhabited when the Spanish arrived; its occupation reaches back to about 1500 BC. Visitors come for its excavated tombs, including Tomb 1 with stucco figures of those buried there.

Mermejita

Mile 357 · Beach · 4 mi from the route · side trip; actual detour depends on access roads

On Oaxaca's central coast just west of Mazunte and San Agustinillo, Mermejita is a small beach village where newcomers have built simple houses from local materials.

More drives to Huatulco

From Cholula to other places in Mexico

Frequently asked questions

How long is the drive from Cholula to Huatulco?

About 7 h 11 min of driving without stops, over 393 miles.

How far is Huatulco from Cholula by car?

About 393 miles (632 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.

Do I need a permit to drive my U.S. car from Cholula to Huatulco?

Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.

Is it safe to drive from Cholula to Huatulco?

The U.S. State Department rates Puebla Level 2: Exercise Increased Caution; Oaxaca Level 2: Exercise Increased Caution (advisory issued May 29, 2026). Read the full advisory before you go.

Which highways go from Cholula to Huatulco?

In order: MEX-190, MEX-150D, MEX-135D, MEX-175, MEX-175D and MEX-200. The road-by-road table above shows the route miles for each one.

Where can you stop on the way from Cholula to Huatulco?

Closest to the road: Museo Nacional de los Ferrocarriles Mexicanos (railway museum, mile 7, 0.5 mi from the route); Museo Rufino Tamayo, Oaxaca (art museum, mile 216, 0.7 mi from the route); Historic centre of Oaxaca (historic center, mile 217, 0.9 mi from the route). All stops are described above.

How we put this guide together

Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.

Route data © OpenStreetMap contributors.