The Wayro route from Cholula to Apatzingán is 375 miles (603 km), about 6 h 7 min of driving without stops.
| Distance | 375 mi (603 km) |
|---|---|
| Driving time, no stops | 6 h 7 min |
| Main roads, in order | MEX-150 → MEX-M40D → MEX-15D → MEX-37D → MEX-14D → MEX-120 |
| Mexican states on the route | Puebla (Level 2), Tlaxcala (Level 2), Hidalgo (Level 2), State of Mexico (Level 2), Michoacán (Level 4) |
| Toll roads | MEX-M40D, MEX-15D, MEX-37D, MEX-14D |
| Fuel estimate (car at 25 mpg) | about 15.0 gal; actual use varies by vehicle and traffic |
| Stops listed below | 9 |
Driving this route in a car with U.S. plates
| Temporary vehicle import permit (TIP) | Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora) |
|---|---|
| Mexican auto insurance | Required for all vehicles: buy a Mexican policy before you drive |
Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.
What the drive from Cholula to Apatzingán is like
MEX-M40D (139 mi) and MEX-15D (90 mi) carry about 61% of the 375 miles. MEX-M40D, MEX-15D, MEX-37D, MEX-14D are toll highways (cuota); MEX-150, MEX-120 are free federal roads (libre). It runs through 5 states: Puebla, Tlaxcala, Hidalgo, State of Mexico, Michoacán. None of the 9 stops below is right on the road, so plan each as a short side trip.
The route from Cholula to Apatzingán, road by road
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–1 | 1 | Puebla |
| MEX-150 | 1–9 | 8 | Puebla |
| local roads | 9–21 | 12 | Puebla |
| MEX-M40D | 21–160 | 139 | Puebla, Tlaxcala, Hidalgo, State of Mexico |
| MEX-15D | 160–250 | 90 | State of Mexico, Michoacán |
| connecting roads | 250–251 | 1 | Michoacán |
| MEX-37D | 251–290 | 39 | Michoacán |
| MEX-14D | 290–318 | 28 | Michoacán |
| MEX-37D | 318–354 | 36 | Michoacán |
| MEX-120 | 354–374 | 20 | Michoacán |
| local roads | 374–375 | 1 | Michoacán |
- Mile 25 of this route: Puebla → Tlaxcala (state line)
- Mile 48 of this route: Tlaxcala → Hidalgo (state line)
- Mile 56 of this route: Hidalgo → State of Mexico (state line)
- Mile 68 of this route: State of Mexico → Hidalgo (state line)
- Mile 85 of this route: Hidalgo → State of Mexico (state line)
- Mile 99 of this route: State of Mexico → Hidalgo (state line)
- Mile 129 of this route: Hidalgo → State of Mexico (state line)
- Mile 178 of this route: State of Mexico → Michoacán (state line)
Stops between Cholula and Apatzingán
- Nature and outdoors: Parque nacional Xicoténcatl (mile 25), Rayón National Park (mile 181), Barranca del Cupatitzio National Park (mile 319)
- Museums and history: Teotihuacan (mile 67), Tula (mile 116), Cathedral of Atlacomulco (mile 161), Museo de Artes e Industrias Populares (mile 293)
Convento de Huejotzingo
Founded by Franciscans in the 16th century, the former convent of San Miguel Arcángel in Huejotzingo shows colonial Plateresque architecture on the western slopes of Popocatépetl and Iztaccíhuatl. UNESCO declared it a World Heritage Site in 1994.
Parque nacional Xicoténcatl
Covering roughly 600 hectares in central Tlaxcala, Xicohténcatl National Park takes in the historic center of Tlaxcala city plus Quiahuixtlán, Ocotelulco and Tepeticpac, which correspond to three of the old Tlaxcalan lordships.
Teotihuacan
Built between the 1st and 7th centuries AD, this UNESCO-listed ancient city lines the Avenue of the Dead, where you can walk between the Pyramid of the Sun, the Pyramid of the Moon and the Temple of the Feathered Serpent.
Tula
Once the Toltec capital, the Tula archaeological zone is best known for its Atlantes, basalt warrior figures over four meters (13 feet) tall crowning the main pyramid. Visitors also see a ball court, the Burnt Palace and the Coatepantli wall, carved with snakes devouring skeletons.
Cathedral of Atlacomulco
Atlacomulco's cathedral, the Catedral de la Divina Providencia, is the seat of the Diocese of Atlacomulco and is dedicated to Divine Providence, making it the town's principal Catholic church.
Rayón National Park
Just outside Tlalpujahua, Rayón National Park (Parque Nacional Rayón) marks the start of the area's famous butterfly reserve country, which stretches south and west from here.
Historic Centre of Morelia
Morelia's old core, founded in the 16th century as Valladolid, keeps more than 200 historic buildings in the region's pink stone around its cathedral and checkerboard streets. UNESCO added it to the World Heritage List in 1991.
Museo de Artes e Industrias Populares
Housed in an 18th-century building adapted from the Colegio de San Nicolás, which Vasco de Quiroga founded in the 16th century, this INAH museum in Pátzcuaro shows Purépecha pottery, textiles, woodwork and lacquerware.
Barranca del Cupatitzio National Park
In Michoacán, Barranca del Cupatitzio National Park follows the headwaters of the Cupatitzio River, which bubbles up from an underground spring and carves a small ravine as it starts to flow.
When you get to Apatzingán
Apatzingán Cathedral
In the city of Apatzingán, Michoacán, the Immaculate Conception Cathedral is a Modernist building that serves as the seat of the local Catholic diocese.
More drives to Apatzingán
- San Juan del Río to Apatzingán
- Mexico City to Apatzingán
- Pachuca to Apatzingán
- San Luis Potosí to Apatzingán
- Cuautla to Apatzingán
- Iguala to Apatzingán
From Cholula to other places in Mexico
- Cholula to Apizaco
- Cholula to Calpulalpan
- Cholula to Otumba
- Cholula to Omitlán
- Cholula to Tepotzotlán
- Cholula to Huasca de Ocampo
Continue Your Adventure
Frequently asked questions
How long is the drive from Cholula to Apatzingán?
About 6 h 7 min of driving without stops, over 375 miles.
How far is Apatzingán from Cholula by car?
About 375 miles (603 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Do I need a permit to drive my U.S. car from Cholula to Apatzingán?
Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.
Is it safe to drive from Cholula to Apatzingán?
The U.S. State Department rates Puebla Level 2: Exercise Increased Caution; Tlaxcala Level 2: Exercise Increased Caution; Hidalgo Level 2: Exercise Increased Caution; State of Mexico Level 2: Exercise Increased Caution; Michoacán Level 4: Do Not Travel (advisory issued May 29, 2026). Read the full advisory before you go.
What roads does the drive from Cholula to Apatzingán use?
In order: MEX-150, MEX-M40D, MEX-15D, MEX-37D, MEX-14D and MEX-120. The road-by-road table above shows the route miles and states for each one.
What are good stops between Cholula and Apatzingán?
Closest to the road: Convento de Huejotzingo (convent, mile 9, 1 mi from the route); Tula (archaeological site, mile 116, 1 mi from the route); Museo de Artes e Industrias Populares (museum, mile 293, 1 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway mile markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route (roughly 2 to 7 miles depending on the type, farther for World Heritage sites): at least one strong stop for each stretch of the drive, then the best-known places nearest the road, with no more than five of one type, up to nine in all. Places that are closed, private or not open to visitors are removed. Place and city descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.