Plan on about 8 h 10 min of driving for the 389-mile (626 km) trip from Berisso to Tacuarembó, Uruguay, before any stops. You cross from Argentina into Uruguay at about mile 243, at the Colón–Paysandú bridge.
Full advisory: Argentina, Uruguay. Advisory issued: Argentina July 10, 2026; Uruguay July 28, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Argentina: “Drivers in Argentina tend to be aggressive, especially in Buenos Aires, and often ignore traffic regulations.”
- Uruguay: “Traffic fatalities are high in Uruguay.”
| Distance | 389 mi (626 km) |
|---|---|
| Time at the wheel, no stops | 8 h 10 min |
| Main roads, in order | 114-05 → RN1 → AV1-N → RN9 → RP6 → RN12 → RN14 → RN135 |
| Border crossing | about mile 243, Argentina → Uruguay (the Colón–Paysandú bridge) |
| Regions on the route | Buenos Aires, Ciudad de Buenos Aires, Entre Ríos, Paysandú, Salto, Tacuarembó |
| Fuel estimate (car at 25 mpg) | about 15.6 gal; actual use varies by vehicle and traffic |
| Stops listed below | 9 |
Getting across the Argentina–Uruguay border
The route crosses at about mile 243, at the Colón–Paysandú bridge, from Entre Ríos into Paysandú. Plan on two checks on each side: immigration for your passport and customs for the car.
| Entering Uruguay (U.S. citizens) | No visa needed for visits of 90 days or less. Passport: must be valid for 6 months beyond your arrival date. |
|---|---|
| Driving in Uruguay | You can drive on your U.S. license. |
| Entering Argentina (U.S. citizens) | No visa needed for visits of 90 days or less. Passport: must be valid when you enter; leave a blank page for the entry and exit stamps. |
| Driving in Argentina | A valid U.S. license usually works; an International Driving Permit is recommended. |
| Rental car | Cross only if the rental company authorizes it in writing and gives you the papers for the border; ask before you book. |
Sources: U.S. State Department, Uruguay (updated August 13, 2026); U.S. State Department, Argentina (updated July 16, 2026). Checked October 10, 2026; rules change, so confirm before you go.
What the drive from Berisso to Tacuarembó is like
RN14 (94 mi) and RN12 (47 mi) carry about 36% of the 389 miles. The first 243 miles are in Argentina; the last 146 are in Uruguay. It runs through 6 regions: Buenos Aires, Ciudad de Buenos Aires, Entre Ríos, Paysandú, Salto, Tacuarembó. Of the 9 stops listed below, 4 are within a mile of the road.
Which roads connect Berisso and Tacuarembó
| Road | Route miles (from–to) | Length, mi | Region |
|---|---|---|---|
| local roads | 0–1 | 1 | Buenos Aires |
| 114-05 | 1–4 | 3 | Buenos Aires |
| connecting roads | 4–7 | 3 | Buenos Aires |
| RN1 | 7–37 | 30 | Buenos Aires, Ciudad de Buenos Aires |
| local roads | 37–40 | 3 | Ciudad de Buenos Aires |
| AV1-N | 40–46 | 6 | Ciudad de Buenos Aires |
| connecting roads | 46–48 | 2 | Ciudad de Buenos Aires |
| RN9 | 48–88 | 40 | Ciudad de Buenos Aires, Buenos Aires |
| RP6 | 88–93 | 5 | Buenos Aires |
| RN12 | 93–140 | 47 | Buenos Aires, Entre Ríos |
| RN14 | 140–234 | 94 | Entre Ríos |
| RN135 | 234–242 | 8 | Entre Ríos |
| local roads | 242–389 | 147 | Entre Ríos, Paysandú, Salto, Tacuarembó |
- Mile 33 of this route: Buenos Aires → Ciudad de Buenos Aires (region line)
- Mile 49 of this route: Ciudad de Buenos Aires → Buenos Aires (region line)
- Mile 110 of this route: Buenos Aires → Entre Ríos (region line)
- Mile 243 of this route: Entre Ríos → Paysandú (international border)
- Mile 351 of this route: Paysandú → Salto (region line)
- Mile 357 of this route: Salto → Paysandú (region line)
- Mile 367 of this route: Paysandú → Tacuarembó (region line)
Breaking up the drive: stops between Berisso and Tacuarembó
- Right off the route (under 1 mile): Museo Ferroviario de Tolosa (mile 7), AMALITA Collection (mile 39), Tierra Santa (mile 44), Museo Carlos Gardel (mile 373)
- Nature and outdoors: Parque Natural Municipal Ribera Norte (mile 52), Pozo Hondo (mile 371)
- Museums and history: Museo Ferroviario de Tolosa (mile 7), AMALITA Collection (mile 39), Museo Carlos Gardel, Buenos Aires (mile 40), Museo Nacional del Hombre (mile 44), Museo Carlos Gardel (mile 373)
- With kids: The Children's Republic (mile 10), Tierra Santa (mile 44)
Museo Ferroviario de Tolosa
Run by the Tolosa branch of the Ferroclub Argentino, created in 1996, the Museo Ferroviario "Ing. Pedro C. Saccaggio" is a railway museum in Tolosa.
The Children's Republic
Spread over 131 acres in La Plata, The Children's Republic is a theme park with 35 scale-model buildings.
AMALITA Collection
Officially the Amalia Lacroze de Fortabat Art Collection, the AMALITA Collection is an art museum in Buenos Aires.
Museo Carlos Gardel, Buenos Aires
Tango singer, composer and film actor Carlos Gardel once lived in the Buenos Aires house that is now the Museo Casa Carlos Gardel.
Tierra Santa
Tierra Santa is a religious theme park in the city of Buenos Aires, in Argentina.
Museo Nacional del Hombre
In the Belgrano district of Buenos Aires, the Museo Nacional del Hombre is a national museum focused on the archaeology of South America's Indigenous peoples.
Parque Natural Municipal Ribera Norte
On the Río de la Plata shore in Acassuso, San Isidro, Ribera Norte is a municipal nature park protecting green space within greater Buenos Aires.
Pozo Hondo
Pozo Hondo is a waterfall in Uruguay's Tacuarembó department, located between the towns of Valle Edén and Tambores.
Museo Carlos Gardel
Dedicated to the life and work of Carlos Gardel, this museum is in Valle Edén, Tacuarembó department, 21 kilometers from the city of Tacuarembó.
Once you reach Tacuarembó
Museo del Deporte
Located in the city of Tacuarembó, Uruguay, the Museo del Deporte preserves and shares the sports history of the Tacuarembó department.
Museo de Geociencias
Museo de Artes Visuales de Tacuarembó
The Museum of Visual Arts of Tacuarembó (Museo de Artes Visuales) is a museum in the city of Tacuarembó, Uruguay.
More drives to Tacuarembó
- Montevideo to Tacuarembó
- Maldonado to Tacuarembó
- Buenos Aires to Tacuarembó, Uruguay
- Rosario, Argentina to Tacuarembó, Uruguay
- Santa Fe to Tacuarembó, Uruguay
- Paraná to Tacuarembó, Uruguay
More drives from Berisso
- Berisso to Adrogué
- Berisso to Tigre
- Berisso to San Antonio de Areco
- Berisso to Arrecifes
- Berisso to Martínez
- Berisso to Colón, Argentina
Continue Your Adventure
Frequently asked questions
How long does it take to drive from Berisso to Tacuarembó, Uruguay?
About 8 h 10 min of driving without stops, over 389 miles.
How far is Tacuarembó, Uruguay from Berisso by car?
About 389 miles (626 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Where does the Berisso to Tacuarembó drive cross the border?
At about mile 243, from Argentina into Uruguay, at the Colón–Paysandú bridge.
What do U.S. citizens need to drive from Berisso into Uruguay?
No visa needed for visits of 90 days or less. Passport: must be valid for 6 months beyond your arrival date. You can drive on your U.S. license. (U.S. State Department, updated August 13, 2026.)
What does the U.S. travel advisory say about the Berisso to Tacuarembó drive?
The U.S. State Department rates Argentina Level 1: Exercise Normal Precautions; Uruguay Level 2: Exercise Increased Caution. Read the full advisory before you go.
What roads does the drive from Berisso to Tacuarembó use?
In order: 114-05, RN1, AV1-N, RN9, RP6, RN12, RN14 and RN135. The road-by-road table above shows the route miles for each one.
What are good stops between Berisso and Tacuarembó?
Closest to the road: AMALITA Collection (art museum, mile 39, 0.3 mi from the route); Tierra Santa (theme park, mile 44, 0.2 mi from the route); Museo Carlos Gardel (museum, mile 373, 0.5 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.