Atlixco to Apizaco Road Trip: Where to Stop on the Way

By admin, 3 October, 2026

The Wayro route from Atlixco to Apizaco is 50 miles (81 km), about 58 min of driving without stops.

U.S. State Department travel advisory: Puebla — Level 2, Exercise Increased Caution; Tlaxcala — Level 2, Exercise Increased CautionAdvisory issued May 29, 2026; checked September 29, 2026. Tlaxcala is the Mexican state that contains Apizaco. See the full advisory for current details.
International Museum of the BaroqueSan Gabriel Franciscan Convent, CholulaMuseo Regional de CholulaConvento de HuejotzingoParque ecológico Los LadrillosLa Malinche National ParkBasílica de OcotlánAtlixcoApizaco
Route from Atlixco to Apizaco with the 7 stops listed below (blue dots).
Distance50 mi (81 km)
Driving time, no stops58 min
Main roads, in orderMEX-190D → MEX-190 → MEX-119D → MEX-117D → MEX-136
Mexican states on the routePuebla (Level 2), Tlaxcala (Level 2)
Toll roadsMEX-190D, MEX-119D, MEX-117D
Fuel estimate (car at 25 mpg)about 2.0 gal; actual use varies by vehicle and traffic
Stops listed below7

Driving this route in a car with U.S. plates

Temporary vehicle import permit (TIP)Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora)
Mexican auto insuranceRequired for all vehicles: buy a Mexican policy before you drive

Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.

What the drive from Atlixco to Apizaco is like

MEX-190D (13 mi) and MEX-119D (12 mi) carry about 50% of the 50 miles. MEX-190D, MEX-119D, MEX-117D are toll highways (cuota); MEX-190, MEX-136 are free federal roads (libre). It runs through 2 states: Puebla, Tlaxcala. Of the 7 stops listed below, 1 are within a mile of the road.

The route from Atlixco to Apizaco, road by road

RoadRoute miles (from–to)Length, miState
local roads0–33Puebla
MEX-190D3–1613Puebla
MEX-19016–259Puebla
MEX-119D25–3712Puebla, Tlaxcala
MEX-117D37–4710Tlaxcala
MEX-13647–503Tlaxcala
  • Mile 29 of this route: Puebla → Tlaxcala (state line)

Stops between Atlixco and Apizaco

  • Right off the route (under 1 mile): Parque ecológico Los Ladrillos (mile 29)
  • Nature and outdoors: Parque ecológico Los Ladrillos (mile 29), La Malinche National Park (mile 40)
  • Museums and history: International Museum of the Baroque (mile 16), Museo Regional de Cholula (mile 21), Basílica de Ocotlán (mile 41)

International Museum of the Baroque

Mile 16 · Art museum · 1 mi from the route

Designed by Japanese architect Toyo Ito and opened in 2016, Puebla's baroque museum wraps its galleries in curving white concrete walls beside a reflecting pond. Exhibits cover baroque painting, sculpture, architecture, music, theater and literature.

San Gabriel Franciscan Convent, Cholula

Mile 21 · Convent · 2 mi from the route

The San Gabriel Franciscan Convent, also called San Gabriel Friary, is a church and friary in Cholula, part of the Puebla metropolitan area.

Museo Regional de Cholula

Mile 21 · Anthropology museum · 1 mi from the route

Right beside the Great Pyramid and archaeological zone of Cholula, this public museum displays collections ranging from pre-Hispanic and colonial art to contemporary and folk art.

Convento de Huejotzingo

Mile 27 · Convent · 9 mi from the route · side trip; actual detour depends on access roads

Founded by Franciscans in the 16th century, the former convent of San Miguel Arcángel in Huejotzingo shows colonial Plateresque architecture on the western slopes of Popocatépetl and Iztaccíhuatl. UNESCO declared it a World Heritage Site in 1994.

Parque ecológico Los Ladrillos

Mile 29 · Park · 0.5 mi from the route

Opened on April 2, 2015, Los Ladrillos Ecological Park is a nature reserve in the municipality of Zacatelco, in Tlaxcala.

La Malinche National Park

Mile 40 · National Park of Mexico · 12 mi from the route · side trip; actual detour depends on access roads

Tlaxcala's La Malinche National Park surrounds the inactive Matlalcuéyetl volcano, with pine, oak and fir forests on its slopes, hiking trails, birdwatching, and stone cabins and campsites at the Malintzi Vacation Center.

Basílica de Ocotlán

Mile 41 · Basilica · 2 mi from the route

On Cerro de San Lorenzo near the city of Tlaxcala, the Basílica de Ocotlán is a standout of Mexican Churrigueresque Baroque, begun in 1670 and home to an ocote-wood image of the Virgin tied to a 1541 legend.

When you get to Apizaco

Basílica de Nuestra Señora de las Misericordias, Apizaco

Basilica · in Apizaco

In the city of Apizaco, this Catholic basilica (Basílica de Nuestra Señora de la Misericordia) was begun in the third decade of the 20th century and completed in 1961.

Ex Convento de Santa María de la Concepción Atlihuetzia

Convent · in Apizaco

The ruined walls of this 16th-century Franciscan convent in Atlihuetzia rise as high as 21 meters beside the 17th-century Purísima Concepción church. The site also holds a sanctuary to Cristóbal, honored as the first Catholic child martyr in the Americas.

Museo Casa de Piedra

Railway museum · in Apizaco

Apizaco's old railroad station, dating from 1916, now houses the Museo Casa de Piedra. Inside, photographs and documents trace the town's history, especially its long ties to the railroads.

More drives to Apizaco

From Atlixco to other places in Mexico

Frequently asked questions

How long is the drive from Atlixco to Apizaco?

About 58 min of driving without stops, over 50 miles.

How far is Apizaco from Atlixco by car?

About 50 miles (81 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.

Do I need a permit to drive my U.S. car from Atlixco to Apizaco?

Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.

Is it safe to drive from Atlixco to Apizaco?

The U.S. State Department rates Puebla Level 2: Exercise Increased Caution; Tlaxcala Level 2: Exercise Increased Caution (advisory issued May 29, 2026). Read the full advisory before you go.

What roads does the drive from Atlixco to Apizaco use?

In order: MEX-190D, MEX-190, MEX-119D, MEX-117D and MEX-136. The road-by-road table above shows the route miles and states for each one.

What are good stops between Atlixco and Apizaco?

Closest to the road: International Museum of the Baroque (art museum, mile 16, 1 mi from the route); Museo Regional de Cholula (anthropology museum, mile 21, 1 mi from the route); Parque ecológico Los Ladrillos (park, mile 29, 0.5 mi from the route). All stops are described above.

How we put this guide together

Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway mile markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route (roughly 2 to 7 miles depending on the type, farther for World Heritage sites): at least one strong stop for each stretch of the drive, then the best-known places nearest the road, with no more than five of one type, up to nine in all. Places that are closed, private or not open to visitors are removed. Place and city descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.

Route data © OpenStreetMap contributors.