Arequipa to Desaguadero Road Trip: Stops Along the Way

By admin, 13 October, 2026

Arequipa to Desaguadero is about 260 road miles (419 km): roughly 8 h 7 min at the wheel if you don't stop.

U.S. State Department travel advisory: Peru — Level 2, Exercise Increased Caution

Full advisory: Peru. Advisory issued: Peru September 04, 2026; checked October 10, 2026.

On the roads, the State Department says:

  • Peru: “Roads are often poorly maintained and may lack crash barriers, guard rails, signs, and streetlights.”
SillustaniCarlos Dreyer MuseumInka TunuwiriInca UyoMollokoArequipaDesaguadero
Route from Arequipa to Desaguadero with the 5 stops listed below (blue dots).
Total distance260 mi (419 km)
Driving time, no stops8 h 7 min
Main roads, in orderAR-116 → PE-34A → PU-121 → PU-1044 → PE-3S
Regions on the routeArequipa, Puno
Fuel estimate (car at 25 mpg)about 10.4 gal; actual use varies by vehicle and traffic
Stops listed below5

On the road from Arequipa to Desaguadero

PE-34A (99 mi) and PE-3S (94 mi) carry about 74% of the 260 miles. It runs through 2 regions: Arequipa, Puno. Of the 5 stops listed below, 4 are within a mile of the road.

Roads you'll take from Arequipa to Desaguadero

RoadRoute miles (from–to)Length, miRegion
local roads0–44Arequipa
AR-1164–3733Arequipa
PE-34A37–13699Arequipa, Puno
PU-121136–14711Puno
PU-1044147–1514Puno
connecting roads151–1521Puno
PU-121152–1586Puno
PE-3S158–1635Puno
local roads163–1718Puno
PE-3S171–26089Puno
  • Mile 83 of this route: Arequipa → Puno (region line)

What to see on the way from Arequipa to Desaguadero

  • Right off the route (under 1 mile): Carlos Dreyer Museum (mile 169), Inka Tunuwiri (mile 177), Inca Uyo (mile 181), Molloko (mile 193)
  • Museums and history: Sillustani (mile 151), Carlos Dreyer Museum (mile 169), Inka Tunuwiri (mile 177), Inca Uyo (mile 181), Molloko (mile 193)

Sillustani

Mile 151 · Archaeological site · 1 mi from the route

On the shores of Lake Umayo near Puno, Sillustani is a pre-Inca burial site with tower-like tombs called chullpas, left by the Qulla people.

Carlos Dreyer Museum

Mile 169 · Museum · 0.4 mi from the route

Puno's Carlos Dreyer Museum (Museo Carlos Dreyer) holds about 1,800 pieces and relics spanning the pre-Inca, Inca, colonial and republican eras, in a building declared part of Peru's national cultural heritage in 1980.

Inka Tunuwiri

Mile 177 · Archaeological site · 0.2 mi from the route

Inka Tunuwiri is an archaeological site in Peru's Puno Province, located between the Chucuito and Puno districts, southeast of the village of Ichu.

Inca Uyo

Mile 181 · Archaeological site · 0.1 mi from the route

Near the Church of Santo Domingo in lakeside Chucuito, Inca Uyo is a rectangular walled enclosure of cut stone holding carved, mushroom-shaped stones. Its original purpose is still debated; Peru declared it national cultural heritage in 2001.

Molloko

Mile 193 · Archaeological site · 0.7 mi from the route

Molloko is an archaeological site in Peru's Puno Province, about 5 kilometers south of the town of Acora, near the village of Molloco.

More drives to Desaguadero

From Arequipa to other places in Peru

Frequently asked questions

How long does it take to drive from Arequipa to Desaguadero?

About 8 h 7 min of driving without stops, over 260 miles.

How far is Desaguadero from Arequipa by car?

About 260 miles (419 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.

What does the U.S. travel advisory say about the Arequipa to Desaguadero drive?

The U.S. State Department rates Peru Level 2: Exercise Increased Caution. Read the full advisory before you go.

What roads does the drive from Arequipa to Desaguadero use?

In order: AR-116, PE-34A, PU-121, PU-1044 and PE-3S. The road-by-road table above shows the route miles for each one.

Where can you stop on the way from Arequipa to Desaguadero?

Closest to the road: Carlos Dreyer Museum (museum, mile 169, 0.4 mi from the route); Inka Tunuwiri (archaeological site, mile 177, 0.2 mi from the route); Inca Uyo (archaeological site, mile 181, 0.1 mi from the route). All stops are described above.

How we put this guide together

Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.

Route data © OpenStreetMap contributors.