Apizaco to Tepoztlán Road Trip: Route, Stops & Safety

By admin, 3 October, 2026

The Wayro route from Apizaco to Tepoztlán is 112 miles (180 km), about 2 h 5 min of driving without stops.

U.S. State Department travel advisory: Tlaxcala — Level 2, Exercise Increased Caution; Puebla — Level 2, Exercise Increased Caution; Morelos — Level 3, Reconsider TravelAdvisory issued May 29, 2026; checked September 29, 2026. Morelos is the Mexican state that contains Tepoztlán. Check the full advisory for this state before you go.
Museo de Sitio de OcotelulcoMuseo Nacional de Antropología e Historia de TlaxcalaGreat Pyramid of CholulaInternational Museum of the BaroqueConvento de Santiago ApóstolLas Pilas archaeological siteMonasteries on the slopes of PopocatépetlTemplo y Exconvento de San Juan Bautista de TlayacapanApizacoTepoztlán
Route from Apizaco to Tepoztlán with the 8 stops listed below (blue dots).
Distance112 mi (180 km)
Driving time, no stops2 h 5 min
Main roads, in orderMEX-117D → MEX-119D → PUE 438D → MEX-160 → MEX-160D
Mexican states on the routeTlaxcala (Level 2), Puebla (Level 2), Morelos (Level 3)
Toll roadsMEX-117D, MEX-119D, MEX-160D
Fuel estimate (car at 25 mpg)about 4.5 gal; actual use varies by vehicle and traffic
Stops listed below8

Driving this route in a car with U.S. plates

Temporary vehicle import permit (TIP)Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora)
Mexican auto insuranceRequired for all vehicles: buy a Mexican policy before you drive

Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.

What the drive from Apizaco to Tepoztlán is like

PUE 438D (34 mi) and MEX-160 (16 mi) carry about 45% of the 112 miles. MEX-117D, MEX-119D, MEX-160D are toll highways (cuota); MEX-160 is a free federal road (libre). It runs through 3 states: Tlaxcala, Puebla, Morelos. Of the 8 stops listed below, 1 are within a mile of the road.

The route from Apizaco to Tepoztlán, road by road

RoadRoute miles (from–to)Length, miState
local roads0–33Tlaxcala
MEX-117D3–1411Tlaxcala
connecting roads14–151Tlaxcala
MEX-119D15–2510Tlaxcala, Puebla
local roads25–4621Puebla
PUE 438D46–8034Puebla, Morelos
MEX-16080–9616Morelos
MEX-160D96–10913Morelos
local roads109–1123Morelos
  • Mile 23 of this route: Tlaxcala → Puebla (state line)
  • Mile 73 of this route: Puebla → Morelos (state line)

Stops between Apizaco and Tepoztlán

  • Right off the route (under 1 mile): Museo de Sitio de Ocotelulco (mile 10)
  • Museums and history: Museo de Sitio de Ocotelulco (mile 10), Museo Nacional de Antropología e Historia de Tlaxcala (mile 11), International Museum of the Baroque (mile 35), Las Pilas archaeological site (mile 81)

Museo de Sitio de Ocotelulco

Mile 10 · Museum · 0.4 mi from the route

Ocotelulco was the principal Tlaxcalan lordship in 1519; its site museum displays about 750 excavated objects beside temple remains painted with Tezcatlipoca and the fire serpent, and an ethnobotanical garden surrounds the building.

Museo Nacional de Antropología e Historia de Tlaxcala

Mile 11 · Museum · 1 mi from the route

Set in the cloisters of Tlaxcala's former Franciscan convent, founded in 1528, the regional museum (Museo Regional de Tlaxcala) traces the state from paleontology and pre-Hispanic cultures through the colonial era to the Revolution, with pottery, sculpture and paintings.

Great Pyramid of Cholula

Mile 32 · Pyramid · 1 mi from the route

Under a hilltop church dedicated to the Virgin of los Remedios lies Tlachihualtepetl, a pyramid built in superimposed stages with a base about 400 meters per side. Excavations have opened roughly 8 km of tunnels inside the mound.

International Museum of the Baroque

Mile 35 · Art museum · 1 mi from the route

Designed by Japanese architect Toyo Ito and opened in 2016, Puebla's baroque museum wraps its galleries in curving white concrete walls beside a reflecting pond. Exhibits cover baroque painting, sculpture, architecture, music, theater and literature.

Convento de Santiago Apóstol

Mile 71 · Convent · 7 mi from the route · side trip; actual detour depends on access roads

In the town of Ocuituco, the Temple and Ex-convent of Santiago Apóstol (Templo y Exconvento de Santiago Apóstol) belongs to the UNESCO-listed group of 16th-century monasteries on the slopes of Popocatépetl, inscribed in 1994.

Las Pilas archaeological site

Mile 81 · Archaeological site · 2 mi from the route · side trip; actual detour depends on access roads

Set inside a bathing park in Jonacatepec, Las Pilas was a ceremonial center devoted to water, where inhabitants built channels to collect and store underground water for irrigation; burials were found within the channel system.

Monasteries on the slopes of Popocatépetl

Mile 99 · World Heritage Site · 6 mi from the route · side trip; actual detour depends on access roads

Inscribed by UNESCO in 1994, this World Heritage site groups early 16th-century monasteries that Franciscan, Dominican and Augustinian friars built on the slopes of Popocatépetl, with large open spaces used to evangelize the Indigenous population.

Templo y Exconvento de San Juan Bautista de Tlayacapan

Mile 103 · Convent · 3 mi from the route · side trip; actual detour depends on access roads

Augustinian friars began this fortress-like church and monastery in the 16th century. Part of the UNESCO-listed group of monasteries on the slopes of Popocatépetl, its former cloister now holds a museum with 17th-century murals and religious art.

When you get to Tepoztlán

Tepoztlán Ex Convento Museum

Museum · in Tepoztlán

Tepoztlán's Dominican monastery, built between 1555 and 1580, keeps original 16th-century murals in its cloister. Upstairs, the museum covers local daily life, faith, festivals and dances, and the complex is part of a UNESCO World Heritage listing.

El Tepozteco National Park

National Park of Mexico · in Tepoztlán

Eroded volcanic hills of the Sierra de Tepoztlán fill this national park, about half of which lies in Mexico City's Milpa Alta borough. A short, steep climb leads to the Tepozteco archaeological zone; wear good shoes, since the rocks get slippery.

Museo Carlos Pellicer

Museum · in Tepoztlán

Tepoztlán's Museo de Arte Prehispánico Carlos Pellicer, opened in 1965 and named for the poet and museographer, displays a collection of pre-Hispanic objects in the former granary of the Church of Nuestra Señora de la Natividad.

More drives to Tepoztlán

From Apizaco to other places in Mexico

Frequently asked questions

How long is the drive from Apizaco to Tepoztlán?

About 2 h 5 min of driving without stops, over 112 miles.

How far is Tepoztlán from Apizaco by car?

About 112 miles (180 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.

Do I need a permit to drive my U.S. car from Apizaco to Tepoztlán?

Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.

Is it safe to drive from Apizaco to Tepoztlán?

The U.S. State Department rates Tlaxcala Level 2: Exercise Increased Caution; Puebla Level 2: Exercise Increased Caution; Morelos Level 3: Reconsider Travel (advisory issued May 29, 2026). Read the full advisory before you go.

What roads does the drive from Apizaco to Tepoztlán use?

In order: MEX-117D, MEX-119D, PUE 438D, MEX-160 and MEX-160D. The road-by-road table above shows the route miles and states for each one.

What are good stops between Apizaco and Tepoztlán?

Closest to the road: Museo de Sitio de Ocotelulco (museum, mile 10, 0.4 mi from the route); Museo Nacional de Antropología e Historia de Tlaxcala (museum, mile 11, 1 mi from the route); International Museum of the Baroque (art museum, mile 35, 1 mi from the route). All stops are described above.

How we put this guide together

Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway mile markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route (roughly 2 to 7 miles depending on the type, farther for World Heritage sites): at least one strong stop for each stretch of the drive, then the best-known places nearest the road, with no more than five of one type, up to nine in all. Places that are closed, private or not open to visitors are removed. Place and city descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.

Route data © OpenStreetMap contributors.